Lexicon for blood-based early detection and screening: BLOODPAC consensus document

The Blood Profiling Atlas in Cancer Consortium (BLOODPAC) has published a new white paper, “Lexicon for blood-based early detection and screening: BLOODPAC consensus document,” in the August issue of Clinical Translational Science.

The authors of this publication identified the need for consensus around definitions for single- and multi-cancer detection (SCD and MCD) tests that harmonize terminology across diverse stakeholders, thereby reducing communication barriers and ultimately advancing the discipline. This work compiles a lexicon of terms, chosen based on perceived importance, frequency of use, lack of clarity and unique challenges in the context of SCD and MCD tests. The lexicon was submitted to the FDA for their feedback, which was incorporated. This publication represents the first installment of the lexicon, consisting of 14 primary terms, that will be part of an online dictionary and provides a foundation for future projects of BLOODPAC.

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